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Year : 2015  |  Volume : 24  |  Issue : 2  |  Page : 137-143

Crystalloid preload shows transient superiority over colloid, or their combination in spinal anaesthesia - induced hypotension prophylaxis for caesarean section

Department of Anaesthesia, University of Benin teaching hospital, Benin city, Edo State, Nigeria

Correspondence Address:
Idehen Hanson Osazuwa
Department of Anaesthesia, University of Benin Teaching Hospital, Benin City, Edo State
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1115-2613.278300

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BACKGROUND Many studies comparing different intravenous fluid types usually do not use equipotent volumes of 3:1 crystalloid: colloid ratio in such comparisons. Conflicting results emanate from such studies.This study was designed to compare the efficacy of equipotent volumes of crystalloid,colloid and combination of crystalloid/colloid in spinal anaesthesia- induced hypotension prophylaxis. METHODOLOGY Pregnant women scheduled for elective Caesarean section were prospectively randomized to three groups to each received either 1500ml of Ringers lactate, or 500 ml of 6% pentastarch or a combination of 250 ml of 6% pentastarch and 750 ml of Ringers lactate intravenous fluid preload,before spinal anaesthesia.Hemodynamic variables were monitored. RESULTS First 10minutes, crystalloid showed better efficacy in hypotension prophylaxis over the other regimen. In the next 30 minutes however, there were no significant differences between the groups. CONCLUSION Crystalloids proved more effective than colloid or their combination in hypotension prophylaxis in the first 10minutes after spinal anaesthesia.

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